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  •  أكتوبر 15, 2025
Stress & Fatigue Screening

In an era where life is moving at a fast pace, many people suffer from symptoms of stress and fatigue without realizing that these feelings may be linked to serious health issues. Therefore, it has become essential to conduct stress and fatigue tests to detect any hormonal or physical imbalances caused by chronic psychological pressure.

In this article, we review the most important tests provided by Advanced Cell Labs in Saudi Arabia.

What is the relationship between stress and physical health?

What is the relationship between stress and physical health?

Chronic stress not only affects mental well-being but can also lead to disorders in the heart, nervous system, and endocrine glands. For example, elevated cortisol levels can cause high blood pressure, sleep disturbances, and immune dysfunction.

 

When do you need a stress test?

You may need stress and fatigue tests if you experience:

  • Persistent fatigue without a clear cause
  • Sleep disturbances
  • Severe mood swings
  • Sudden heart palpitations
  • Reduced concentration and memory

Best laboratory for tests in Saudi Arabia - Advanced Cell Lab

Cortisol Hormone Test

The cortisol test measures the level of this hormone secreted by the adrenal gland, known as the “stress hormone,” which helps the body cope with physical and psychological stress.

The test is often requested in the morning when cortisol levels are highest, and may be repeated in the evening for comparison. It helps diagnose conditions such as Addison’s disease (low cortisol) or Cushing’s syndrome (high cortisol).

The test can be performed using blood, urine, or saliva, and factors such as stress, medications, and sleep can affect accuracy. Therefore, follow your doctor’s instructions before the test.

 

Adrenaline and Noradrenaline Tests

The adrenaline (Adrenaline) and noradrenaline (Noradrenaline) tests measure hormone levels secreted by the adrenal gland in response to stress or danger, known as the “fight or flight” hormones.

The test is usually conducted via 24-hour urine collection or blood sample and is used to diagnose disorders such as adrenal gland tumors (e.g., pheochromocytoma) or unexplained high blood pressure.

It is important to stop certain medications and caffeine before testing, as they can affect results. Below is a simplified table comparing adrenaline and noradrenaline in terms of function, source, and body effects:

Comparison Adrenaline Noradrenaline
Other Name Epinephrine Norepinephrine
Source Adrenal gland (medulla) Sympathetic nerve endings + adrenal gland
Main Function Stimulates the body during stress or danger (fight or flight) Regulates blood pressure and increases blood flow to organs
Effect on Heart Increases heart rate Increases heart contraction strength
Effect on Blood Vessels Dilates vessels in muscles and constricts in skin Constriction of blood vessels to raise blood pressure
Effect on Respiration Dilates airways Less effect on respiratory system
Response to Stress Fast and strong More stable and sustained
Medical Use Treat severe allergies (anaphylaxis) and asthma Treat severe hypotension

Note: Abnormally high levels of either hormone may indicate an adrenal gland tumor; hence, these tests are used for diagnosis.

 

Adrenal Gland Tests

Adrenal Gland Tests

The adrenal gland is responsible for secreting cortisol and adrenaline. Function tests help detect diseases such as Cushing’s syndrome or adrenal insufficiency.

Sleep Tests

Sleep disturbances are often indicators of stress. Activity tracking devices can evaluate sleep quality and detect chronic insomnia.

Blood Pressure and Its Variations

Sudden or sustained high blood pressure is a sign of chronic stress. Regular monitoring can reveal the effects of stress on the heart and blood vessels.

Resting Heart Rate Test

An elevated resting heart rate may indicate ongoing psychological or physical stress.

 

How to interpret stress test results?

Doctors interpret results based on normal ranges for each test and consider the patient’s medical history and accompanying symptoms. Prolonged elevated cortisol or adrenaline levels should not be ignored.

Difference Between Physical and Psychological Stress

  • Physical Stress: Results from physical fatigue or chronic illness.
  • Psychological Stress: Related to emotional and mental state, affecting hormones and immunity. Both types can cause overlapping symptoms and require targeted tests to determine the exact cause.

Does stress affect other tests?

Yes. Stress may alter results of tests such as blood sugar, blood pressure, thyroid function, and general blood tests. Therefore, it is important to inform your doctor of any psychological stress before testing.

 

Tips Before and After Testing

  • Avoid caffeine before testing.
  • Try to relax for at least 30 minutes before sampling.
  • Inform your doctor of any medications or supplements you take.
  • After testing, discuss results with your doctor to determine a stress management plan.

 

Frequently Asked Questions About Stress Tests

1. Can stress be measured accurately?
Yes, through hormonal tests such as cortisol and sleep tests.

2. Can stress cause chronic diseases?
Yes, chronic stress can lead to heart disease, diabetes, and immune disorders.

3. How often should stress be tested?
It depends on symptoms and medical history, but testing is recommended when experiencing persistent fatigue or health changes.

 

Stress and fatigue tests are an important step in maintaining the balance of your physical and mental health. Don’t wait until symptoms worsen—take the appropriate tests at Advanced Cell Labs to receive an accurate and comprehensive evaluation of your condition. Book your appointment now and start your journey towards a healthier, more balanced life.

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